Carbon tetrachloride induced hepatorenal toxicity in rats: possible protective effects of wild Pleurotus tuber-regium

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Carbon tetrachloride induced hepatorenal toxicity in rats: possible protective effects of wild Pleurotus tuber-regium

Background: The economic cost of and liver and kidney diseases in Sub Saharan Africa remain prohibitive, hence the quest for medicinal foods that can reverse hepato-renal damages. The aim of this study is to investigate the hepato-renal protective effect of wild edible P.tuber-regium on carbon tetrachloride (CCl4) induced oxidative stress in male Sprague–Dawley rats. Method: Thirty six rats wer...

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Protective Effects of Pleurotus tuber-regium on Carbon- Tetrachloride Induced Testicular Injury in Sprague Dawley Rats

The high rate of male infertility and the meager resources to manage same in sub Saharan Africa have necessitated the search for cost effective and available alternatives. Mushrooms have been used traditionally in folk medicine and as nutraceuticals. This study has investigated the effect of the wild mushroom Pleurotus tuber-regium on carbon tetrachloride (CCl4) deleterious effects on the repro...

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Pleurotus tuber-regium mushrooms in the diet of rats ameliorates reproductive and testicular injury caused by carbon tetrachloride

Background: The incidence of male infertility arising from male sexual dysfunction is high especially in the sub saharan Africa. African foods may hold promise to reverse this trend. The aim of this study therefore is to evaluate the improvement of the reproductive and testicular injuries mediated by CCl4 by the use of a wild edible mushroom, P. tuber-regium. Methods: Sixty rats were divide int...

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The Protective Effect of Croton zambesicus against Carbon Tetrachloride-induced Renal Toxicity in Rats

Background: The leaf extract of Croton zambesicus (CZ) is used in traditional medicine for the management of various conditions including kidney disease. The purpose of this study was to determine the protective effects of leaf extract of CZ on rat kidney toxicity induced by carbon tetrachloride. Method: Male albino rats were divided into 6 groups of 5 rats and treated for 5 days with aqueous ...

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The Possible protective effects of Physalis peruviana on carbon tetrachloride-induced nephrotoxicity in male albino rats

Physalis peruviana (physalis) has long held a place in folk medicine in the tropical countries where it grows. Here, the aim of this study was to evaluate the potential nephroprotective impact of physalis extract against carbon tetrachloride (CCl4)-induced kidney injury and to explore the possible mechanisms by which this plant exerts its beneficial effects. Rats were randomly divided into equa...

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ژورنال

عنوان ژورنال: Clinical Phytoscience

سال: 2017

ISSN: 2199-1197

DOI: 10.1186/s40816-016-0040-5